2008 Kelman Award Recipient
INSTITUTE:
University of Kentucky
Dr. Kleinman is described as an unusually talented and highly motivated young physician-scientist. His fascination with vascular biology flourished in a high school summer research program at the Milwaukee Heart Project and continued at Emory University in Atlanta, Georgia where he joined The Greuntzig Laboratory for Interventional Cardiology and participated in several catheter-based biomedical engineering studies with an emphasis in intravascular brachytherapy. During his medical education at New York University (NYU), which included a pre-doctoral fellowship, Kleinman implemented a translational program in the Laboratory of Microvascular Research and Vascular Tissue Engineering under the direction of Dr. Geoffrey Gurtner. It was here that he began to develop his ability to formulate approaches to scientifically address unanswered questions of clinical relevance.
Kleinman’s research at NYU significantly contributed to the field of endothelial stem/progenitor cell biology and anomalous vascular growth, in particular with the enigmatic clinical presentation of proliferating infantile hemangioma, for which he was awarded the Weston Research Grant. These findings were published in a wide array of scientific journals and include a seminal first-authored manuscript on hypoxia-induced mediators of progenitor cell trafficking in infantile hemangioma in the AHA publication, Atherosclerosis, Thrombosis, and Vascular Biology, which featured the article on the cover of the issue.
Publications by this Author:
Mark E. Kleinman, BS, MD — 2008
1/1/08
PROJECT TITLE:
The Heterogeneous Immunovascular Effects of siRNA in the Posterior Segment